Loading...

APC/Cyanine7 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, κ APC/Cyanine7 isotype control (open histogram).
  • 30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
    C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, κ APC/Cyanine7 isotype control (open histogram).
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
103115 25 µg 79€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
103116 100 µg 157€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  2. Contijoch EJ et al. 2019. eLife. 8 pii: e40553. PubMed
  3. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  4. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  5. Ren Y, et al. 2021. Am J Transplant. 21:552. PubMed
  6. Hilfenhaus G, et al. 2021. Cancer Res. 81:619. PubMed
  7. Bruno MEC, et al. 2022. J Cell Physiol. 237:706. PubMed
  8. Cohen K, et al. 2021. Cell Rep. 37:110026. PubMed
  9. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  10. He D, et al. 2022. Immunity. 55:159. PubMed
  11. Alam A, et al. 2022. Cancer Cell. 40:153. PubMed
  12. Goncharov NV, et al. 2022. J Evol Biochem Physiol. 58:230. PubMed
  13. Li DD, et al. 2022. J Cell Mol Med. 26:2438. PubMed
  14. Denorme F, et al. 2022. J Clin Invest. 132: . PubMed
  15. Tang Q, et al. 2022. Mol Ther. 30:2709. PubMed
  16. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  17. Miyao T, et al. 2022. Elife. 11: . PubMed
  18. Serra M, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:609. PubMed
  19. Poh AR, et al. 2022. Sci Adv. 8:eabl7882. PubMed
  20. Campisi L, et al. 2022. Nature. 606:945. PubMed
  21. Kenigsbuch M, et al. 2022. Nat Neurosci. 25:876. PubMed
  22. Zhao Z, et al. 2022. Adv Sci (Weinh). 9:e2201293. PubMed
  23. Li F, et al. 2022. Gut Microbes. 14:2096989. PubMed
  24. Rodrigues PB, et al. 2022. Cells. 11: . PubMed
  25. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  26. Poh AR, et al. 2022. Cell Rep. 41:111479. PubMed
  27. Zhu X, et al. 2023. Adv Mater. 35:e2207198. PubMed
  28. Li S, et al. 2022. Nat Commun. 13:7371. PubMed
  29. Morrow RJ, et al. 2022. Cells. 11: . PubMed
  30. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  31. Alula KM, et al. 2023. Sci Rep. 13:18. PubMed
  32. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  33. Montilla A, et al. 2023. Cell Death Dis. 14:16. PubMed
  34. Zhou J, et al. 2023. Nutrients. 15: . PubMed
  35. Slusarczyk P, et al. 2023. Elife. 12: . PubMed
  36. Cao Y, et al. 2023. J Inflamm Res. 16:343. PubMed
  37. Tsioti I, et al. 2023. J Neuroinflammation. 20:25. PubMed
  38. Li XF, et al. 2023. J Exp Med. 220: . PubMed
  39. Chun J, et al. 2023. Cancers (Basel). 15: . PubMed
  40. Drummer C, et al. 2023. Front Immunol. 14:1113883. PubMed
  41. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  42. Ryan CB, et al. 2022. Neurobiol Dis. 163:105608. PubMed
  43. Marsh SE, et al. 2022. Nat Neurosci. 25:306. PubMed
  44. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  45. Hailemichael Y, et al. 2022. Cancer Cell. 40:509. PubMed
  46. Korsunsky I, et al. 2022. Med. 3:481. PubMed
  47. Cheng C, et al. 2022. Cell Mol Gastroenterol Hepatol. 15:261. PubMed
  48. Pattwell SS, et al. 2022. Sci Adv. 8:eabo6789. PubMed
  49. Schroeter CB, et al. 2022. J Neuroinflammation. 19:270. PubMed
  50. Ho HM, et al. 2022. Pharmaceutics. 14:. PubMed
  51. Cai Z, et al. 2023. Adv Sci (Weinh). 10:e2207155. PubMed
  52. Banerjee K, et al. 2023. Eur J Immunol. 53:e2250161. PubMed
  53. Wu Z, et al. 2023. EMBO Rep. 24:e56524. PubMed
  54. Gao L, et al. 2023. J Nanobiotechnology. 21:56. PubMed
  55. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  56. Lu C, et al. 2023. Antiviral Res. 212:105556. PubMed
  57. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  58. Saha S, et al. 2023. Sci Rep. 13:4609. PubMed
  59. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  60. Freitag PC, et al. 2023. Mol Ther Methods Clin Dev. 29:120. PubMed
  61. Thai LM, et al. 2023. iScience. 26:106477. PubMed
  62. He Q, et al. 2023. Parasit Vectors. 16:139. PubMed
  63. Sasaki L, et al. 2022. Nat Aging. 2:105. PubMed
  64. Haensel D, et al. 2023. Nat Commun. 14:2685. PubMed
  65. Lee K, et al. 2023. JCI Insight. 8:. PubMed
  66. Wang C, et al. 2023. Int J Oral Sci. 15:19. PubMed
  67. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  68. Scieszka DP, et al. 2023. Respir Res. 24:138. PubMed
  69. Yang QC, et al. 2023. iScience. 26:106916. PubMed
  70. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  71. Stefkovich M, et al. 2021. Mol Metab. 54:101357. PubMed
  72. Wang Q, et al. 2020. Radiat Environ Biophys. 59:89. PubMed
  73. Kim MY, et al. 2021. JCI Insight. 6:. PubMed
  74. De Vries LCS, et al. 2021. J Crohns Colitis. 15:617. PubMed
  75. Bernasconi R, et al. 2021. EMBO Mol Med. :e14392. PubMed
  76. Miranda K, et al. 2022. iScience. 25:104994. PubMed
  77. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  78. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  79. Ren D, et al. 2022. STAR Protoc. 3:101217. PubMed
  80. Chang YS, et al. 2020. Int J Mol Sci. 21:00. PubMed
  81. Naito H, et al. 2020. Nature Protocols. 15(3):1066-1081. PubMed
  82. Xing J, et al. 2021. Cell Reports. 35(12):109205. PubMed
  83. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  84. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  85. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  86. Page N, et al. 2018. Immunity. 48:937. PubMed
  87. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  88. Ajina R, et al. 2019. Oncoimmunology. 8:e1577127. PubMed
  89. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  90. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  91. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  92. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  93. Wu SY, et al. 2022. Mol Cancer. 21:84. PubMed
  94. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  95. Jiang Q, et al. 2022. Theranostics. 12:59. PubMed
  96. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  97. Fan L, et al. 2021. Cancers (Basel). 13:. PubMed
  98. Urban SK, et al. 2020. Liver Int. 40:3103. PubMed
  99. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  100. Rosenkranz SC, et al. 2021. eLife. 10:00. PubMed
  101. Kokona D, et al. 2016. Exp Eye Res. S0014-4835(16)30499-7. PubMed
  102. Ebneter A, et al. 2017. Transl Vis Sci Technol. 10.1167/tvst.6.2.10. PubMed
  103. Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
  104. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  105. Blecher-Gonen R, et al. 2019. Cell Syst. 8:109. PubMed
  106. Zhu S, et al. 2022. Front Pharmacol. 13:996635. PubMed
  107. Palacios LM, et al. 2022. Biology (Basel). 11:. PubMed
  108. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  109. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  110. Adrover JM, et al. 2022. JCI Insight. 7:. PubMed
  111. Steubing RD, et al. 2022. Brain Behav Immun Health. 24:100493. PubMed
  112. Lu H, et al. 2021. Autophagy. 17:2511. PubMed
  113. Kawashima N, et al. 2022. Nat Commun. 13:1624. PubMed
  114. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  115. Uzhachenko RV, et al. 2021. Cell Reports. 35(1):108944. PubMed
  116. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  117. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  118. Baram T, et al. 2021. Cells. 10:. PubMed
  119. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  120. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  121. Evans H, et al. 2015. J Immunol. 195: 2973 - 2984. PubMed
  122. Cardona S, et al. 2015. ASN Neuro. 7: 1759091415608204. PubMed
  123. Kashyap AS, et al. 2019. Cell Rep. 28:3367. PubMed
  124. Pluchino N, et al. 2020. J Cell Mol Med. 24:2464. PubMed
  125. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  126. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  127. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  128. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  129. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  130. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  131. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  132. Biswas S, et al. 2021. Nature. 591:464. PubMed
  133. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  134. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  135. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  136. Ganeshan K et al. 2019. Cell. 177(2):399-413 . PubMed
  137. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  138. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  139. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  140. Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
  141. Jung BG, et al. 2022. PLoS Pathog. 18:e1010454. PubMed
  142. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  143. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  144. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  145. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  146. Yoon Y, et al. 2021. Cancers (Basel). 13: . PubMed
  147. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  148. Shibata K, et al. 2014. J Immunol. 192:2210. PubMed
  149. Mantia-Smaldone G, et al. 2014. Gynecol Oncol. 133:584. PubMed
  150. Rybalko V, et al. 2015. PLoS One. 10: 0145550. PubMed
  151. AR P, et al. 2016. Circ Res. 118: 400-409. PubMed
  152. Wiley CD, et al. 2019. JCI Insight. 4:e130056. PubMed
  153. Krasteva G, et al. 2011. Proc Natl Acad Sci U S A. 108:9478. PubMed
  154. Higashi AY, et al. 2019. J Am Soc Nephrol. 30:80. PubMed
  155. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  156. Evans R, et al. 2019. Cell Rep. 27:1967. PubMed
  157. Hammond TR, et al. 2019. Immunity. 50:253. PubMed
  158. Schönfeld M, et al. 2021. Alcohol Clin Exp Res. 45:1980. PubMed
  159. Bhattacherjee A, et al. 2021. Mol Neurodegener. 16:19. PubMed
  160. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  161. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  162. Marangoni F, et al. 2021. Cell. . PubMed
  163. Wang LT, et al. 2021. STAR Protocols. 2(1):100337. PubMed
  164. Fachi JL, et al. 2020. J Exp Med. 217:00:00. PubMed
  165. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  166. Cordeiro O, et al. 2016. PLoS One. 11: 0151848. PubMed
  167. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  168. Huang B, et al. 2020. Cell. 179(5):1160-1176.e24.. PubMed
  169. Ning F, et al. 2019. J Exp Med. 216:1396. PubMed
  170. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  171. Commerford CD et al. 2018. Cell reports. . PubMed
  172. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  173. Yousef H, et al. 2018. Bio Protoc. 8:22. PubMed
  174. Willingham SB, et al. 2018. Cancer Immunol Res. 6:1136. PubMed
  175. Donlan AN, et al. 2020. Anaerobe. 66:102275. PubMed
  176. Uher O, et al. 2021. Cancers (Basel). 13:. PubMed
  177. Liu M, et al. 2020. Cell Rep. 32:107990. PubMed
  178. Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
  179. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  180. Chi Z, et al. 2020. Molecular Cell. 80(1):43-58.e7. PubMed
  181. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  182. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  183. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  184. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  185. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  186. Hillel–Karniel C, et al. 2020. Cell Reports. 30(3):807-819.e4.. PubMed
  187. Li Y, et al. 2019. Sci Rep. 9:6932. PubMed
  188. Mifflin L, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  189. Stewart JM, et al. 2020. ACS Biomater Sci Eng. 6:5941. PubMed
  190. Gao H, et al. 2021. Cells. 10:. PubMed
  191. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  192. Ajina R, et al. 2021. Cancer Immunol Res. 9:386. PubMed
  193. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  194. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  195. Zhang X, et al. 2020. Elife. 9:00. PubMed
  196. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  197. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  198. Chun E, et al. 2020. Immunity. 51(5):871-884.e6.. PubMed
  199. Bahar Halpern K, et al. 2020. Nat Commun. 11:1936. PubMed
  200. Soldevilla MM, et al. 2019. Mol Ther. 27:1878. PubMed
  201. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  202. Ayaub E,et al. 2017. Sci Rep.. 10.1038/s41598-017-13511-z. PubMed
  203. Peralta Ramos JM, et al. 2017. Front Immunol. 1.490277778. PubMed
  204. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  205. Alikhanyan K, et al. 2021. Cancers (Basel). 13:. PubMed
  206. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  207. Ali M, et al. 2022. JCI Insight. 7:. PubMed
  208. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  209. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  210. Ghandhi SA, et al. 2022. Sci Rep. 12:14124. PubMed
  211. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  212. Fu H, et al. 2020. Front Immunol. 11:595813. PubMed
  213. Oladiran O, et al. 2021. J Neuroinflammation. 77:18. PubMed
  214. Veremeyko T, et al. 2012. J Vis Exp. 65: 4097. PubMed
  215. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  216. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  217. Neuhöfer P, et al. 2021. Nature. 597:715. PubMed
  218. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  219. Hum NR, et al. 2022. Front Oncol. 12:928474. PubMed
  220. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  221. Selvaraj UM, et al. 2021. Brain Behav Immun. 95:502. PubMed
  222. Ying T, et al. 2021. Am J Physiol Endocrinol Metab. 320:E1148. PubMed
  223. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  224. Momin N, et al. 2022. Nat Commun. 13:109. PubMed
  225. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  226. Pilones KA, et al. 2020. Cancer Immunol Res. 8:1054. PubMed
  227. Toubal A, et al. 2020. Nat Commun. 3755:11. PubMed
  228. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  229. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  230. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  231. Martina M, et al. 2014. J Vis Exp. 87: 51192. PubMed
  232. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  233. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  234. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  235. Yang Y, et al. 2022. Elife. 11:. PubMed
  236. Dhanwani R, et al. 2020. Sci Adv. 6:eaba3688. PubMed
  237. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  238. Cardenas JJ, et al. 2020. Methods Enzymol. 415:631. PubMed
  239. Abramowski P, et al. 2014. J Neuroimmunol. 274:111. PubMed
  240. Hoeksema M, et al. 2015. J Immunol. 194:3909. PubMed
  241. Alikhanyan K, et al. 2020. Immun Inflamm Dis. 8:181. PubMed
  242. Cheng Y, et al. 2019. Clin Cancer Res. 25:2621. PubMed
  243. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  244. Wang R, et al. 2022. Front Immunol. 13:947756. PubMed
  245. Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
  246. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  247. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  248. Clement CC, et al. 2021. Nat Commun. 12:4447. PubMed
  249. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  250. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  251. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  252. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  253. Gierut J, et al. 2015. Stem Cell Res. 15: 165-171. PubMed
  254. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  255. Haka A, et al. 2012. PLoS One. 7:e44823. PubMed
  256. Kaya B, et al. 2020. Cell Reports. 32(5):107979. PubMed
  257. Sztwiertnia I, et al. 2020. PLoS One. 15:e0233789. PubMed
  258. Veremeyko T, et al. 2019. J Neurosci Res. 97:162. PubMed
  259. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  260. Kim MY, et al. 2018. Cell. 173:1439. PubMed
  261. Li D, et al. 2022. Emerg Microbes Infect. 11:2248. PubMed
  262. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  263. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  264. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  265. Zhang R, et al. 2022. Front Pharmacol. 13:870848. PubMed
  266. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  267. Huetter J, et al. 2020. Cancer Immunol Res. 0.954861111. PubMed
  268. Favuzzi E, et al. 2021. Cell. 184(15):4048-4063.e32. PubMed
  269. DiToro D, et al. 2020. Immunity. 650:52. PubMed
  270. Camara A, et al. 2019. Immunity. 50:1467. PubMed
  271. Michaelis KA, et al. 2019. Brain Behav Immun. 82:338. PubMed
  272. Yuan X, et al. 2017. Elife. 6:e29540. PubMed
  273. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  274. Selvaraj UM et al. 2018. Endocrinology. 159(11):3848-3859 . PubMed
  275. Pinho–Ribeiro FA, et al. 2018. Cell. 173:1083. PubMed
  276. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  277. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  278. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  279. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  280. Wang X, et al. 2022. Front Immunol. 13:864984. PubMed
  281. Galani IE, et al. 2022. STAR Protoc. 3:101151. PubMed
  282. Abdelfattah N, et al. 2022. Nat Commun. 13:767. PubMed
  283. Ou YC, et al. 2020. ACS Nano. 1.035416667. PubMed
  284. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  285. Zelco A, et al. 2020. Front Cell Neurosci. 0.75625. PubMed
  286. Wang LT, et al. 2020. Cell Rep. 32:108188. PubMed
  287. Hadas R, et al. 2020. JCI Insight. 5:00. PubMed
  288. Stock M, et al. 2015. Osteoarthritis Cartilage. 23: 1221-1225. PubMed
  289. Draper D, et al. 2012. J Immunol. 188:5327. PubMed
  290. Hohsfield LA, et al. 2020. J Neuroinflammation. 0.902083333. PubMed
  291. Godwin MS, et al. 2019. JCI Insight. 4:e126070. PubMed
  292. Wakabayashi T et al. 2018. Cell stem cell. 22(3):384-397 . PubMed
  293. Kaiser T, et al. 2019. Eneuro. 6. PubMed
  294. El Agha E, et al. 2017. Cell Stem Cell. 1.014583333. PubMed
  295. Bhatt D, et al. 2021. J Exp Med. 218:. PubMed
  296. Lu Z, et al. 2021. J Clin Invest. 131:. PubMed
  297. Luo M, et al. 2021. J Immunol. 207:1683. PubMed
  298. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  299. Martina M, et al. 2016. J Am Soc Nephrol. 27: 1113-1123. PubMed
  300. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  301. Ben-Moshe S, et al. 2019. Nat Metab. 1:899. PubMed
  302. Ji L et al. 2019. Immunity. 51(2):272-284 . PubMed
  303. Jiang P, et al. 2018. Nat Med. 24:1550. PubMed
  304. Wang X, et al. 2018. Nat Commun. 9:551. PubMed
  305. Li N, et al. 2022. Nat Commun. 13:7281. PubMed
  306. Pedicone C, et al. 2022. iScience. 25:104170. PubMed
  307. Godwin MS, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 320:L393. PubMed
  308. Reda M, et al. 2022. Nat Commun. 13:4261. PubMed
  309. Li Y, et al. 2022. STAR Protoc. 3:101364. PubMed
  310. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  311. Milich LM, et al. 2021. J Exp Med. 218:. PubMed
  312. Kline JM, et al. 2021. J Biol Chem. :100373. PubMed
  313. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  314. Starikova E, et al. 2021. Front Pharmacol. 12:667572. PubMed
  315. Klein S, et al. 2016. J Cell Sci. 129: 2573 - 2585. PubMed
  316. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  317. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  318. Armaka M, et al. 2018. Nat Commun. 9:618. PubMed
  319. Lang JF et al. 2019. Nat Commun. 10(1):3415 . PubMed
  320. Theurich S et al. 2017. Cell metabolism. 26(1):171-184 . PubMed
  321. Martin A, et al. 2018. Oncotarget. 9:28364. PubMed
  322. Yan C, et al. 2022. NPJ Precis Oncol. 6:6. PubMed
  323. Phansalkar R, et al. 2021. Elife. 10:. PubMed
  324. Kim S, et al. 2022. Cancers (Basel). 14:. PubMed
  325. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  326. Lu C, et al. 2020. Cancer Cell. 39(1):96-108.e6. PubMed
  327. Yang C, et al. 2020. Cell Host Microbe. 467:27. PubMed
  328. Morein D, et al. 2021. Cells. 10: . PubMed
  329. Yoldi G, et al. 2016. Cancer Res . 76: 5857 - 5869. PubMed
  330. Ling Y, et al. 2016. Pharmacol Res. S1043-6618(16)31329-9. PubMed
  331. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  332. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  333. Ireland L, et al. 2020. Front Immunol. 11:297. PubMed
  334. Gago-Lopez N, et al. 2019. EMBO Mol Med. 11:e10697. PubMed
  335. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  336. Uluçkan ö, et al. 2020. Cell Reports. 29(4):844-859.e3.. PubMed
  337. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  338. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  339. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  340. Wang Y, et al. 2022. Nat Commun. 13:1454. PubMed
  341. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  342. Zhang X, et al. 2022. J Exp Clin Cancer Res. 41:246. PubMed
  343. Guan D, et al. 2021. Cell Death Dis. 12:431. PubMed
  344. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  345. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  346. Wang J, et al. 2021. Am J Cancer Res. 11:2005. PubMed
  347. Wang X, et al. 2021. Theranostics. 11:209. PubMed
  348. Liu SS, et al. 2021. Immunity. :. PubMed
  349. Ukidve A, et al. 2020. Proc Natl Acad Sci U S A. 117:17727. PubMed
  350. E O’Koren, R Mathew, D Saban 2016. Sci Rep. 6:20636. PubMed
  351. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  352. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  353. Seeling M, et al. 2013. Proc Natl Acad Sci U S A. 110:10729. PubMed
  354. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  355. Fransén Pettersson N, et al. 2018. PLoS One. 13:e0203228. PubMed
  356. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  357. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  358. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  359. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  360. Sebastian A, et al. 2021. Cells. 10:. PubMed
  361. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  362. Chen MB, et al. 2020. Cell Rep. 30:4418. PubMed
  363. Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
  364. Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
  365. Cong L, et al. 2021. Breast Cancer Res. 23:51. PubMed
  366. De Micheli AJ, et al. 2020. Am J Physiol Cell Physiol. 319:C885. PubMed
  367. Sibler E, et al. 2021. Cells. 10:. PubMed
  368. Oladiran O, et al. 2021. Front Immunol. 12:720733. PubMed
  369. Lux A, et al. 2014. Cell Rep. 10:236. PubMed
  370. Madsen P, et al. 2016. J Neurosci. 36: 5128 - 5143. PubMed
  371. Fox B, et al. 2016. PLoS One. 12: 1006189. PubMed
  372. Parker K, Horn L, Ostrand-Rosenberg S 2016. J Leukoc Biol. 100: 463 - 470.. PubMed
  373. Forte E, et al. 2020. Cell Rep. 30:3149. PubMed
  374. Wang J, et al. 2020. J Hematol Oncol. 0.610416667. PubMed
  375. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  376. Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
  377. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  378. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  379. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  380. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  381. Sun D, et al. 2020. PLoS Pathog. 16:e1008361. PubMed
  382. Zhu Q, et al. 2021. J Am Heart Assoc. 10:e023491. PubMed
  383. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
  384. Parent AV, et al. 2021. Cell Reports. 36(7):109538. PubMed
  385. Ito Y, et al. 2021. Cell Reports. 35(4):109052. PubMed
  386. Ma Y, et al. 2021. Developmental Cell. 56(4):478-493.e11. PubMed
  387. Ye Y, et al. 2020. Genome Med. 0.557638889. PubMed
  388. Campisi L, et al. 2016. Nat Immunol. 10.1038/ni.3512. PubMed
  389. Holzapfel B, et al. 2015. Biomaterials. 61: 103-114. PubMed
RRID
AB_312980 (BioLegend Cat. No. 103115)
AB_312981 (BioLegend Cat. No. 103116)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Go To Top Version: 3    Revision Date: 01-30-2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account