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FITC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-f11
C57BL/6 splenocytes stained with 30-F11 FITC
  • 30-f11
    C57BL/6 splenocytes stained with 30-F11 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103107 50 µg 29€
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103108 500 µg 84€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  2. Sefik E, et al. 2022. Nature. 606:585. PubMed
  3. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  4. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  5. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  6. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  7. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  8. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  9. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  10. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  11. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  12. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  13. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  14. Zheng Z, et al. 2022. Cells. 11: . PubMed
  15. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  16. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  17. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  18. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  19. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  20. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  21. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  22. Liu X, et al. 2022. Pain. 163:508. PubMed
  23. González H, et al. 2022. Cell. 185:729. PubMed
  24. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  25. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  26. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  27. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  28. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  29. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  30. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  31. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  32. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  33. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  34. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  35. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  36. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  37. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  38. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  39. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  40. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  41. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  42. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  43. Li L, et al. 2023. iScience. 26:106095. PubMed
  44. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  45. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  46. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  47. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  48. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  49. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  50. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  51. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  52. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  53. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  54. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  55. Wang X, et al. 2023. Nature. 618:808. PubMed
  56. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  57. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  58. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  59. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  60. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  61. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  62. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  63. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  64. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  65. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  66. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  67. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  68. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  69. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  70. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  71. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  72. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  73. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  74. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  75. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  76. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  77. Zhu H, et al. 2018. Elife. 7:. PubMed
  78. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  79. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  80. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  81. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  82. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  83. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  84. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  85. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  86. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  87. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  88. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  89. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  90. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  91. Saito S, et al. 2020. Nutrients. 12:. PubMed
  92. Liu X, et al. 2020. Nature. . PubMed
  93. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  94. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  95. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  96. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  97. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  98. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  99. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  100. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  101. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  102. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  103. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  104. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  105. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  106. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  107. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  108. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  109. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  110. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  111. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  112. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  113. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  114. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  115. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  116. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  117. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  118. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  119. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  120. Plein A, et al. 2018. Nature. 562:223. PubMed
  121. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  122. Green DP, et al. 2019. Neuron. 101:412. PubMed
  123. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  124. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  125. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  126. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  127. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  128. Zhang X, et al. 2022. Cells. 11:. PubMed
  129. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  130. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  131. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  132. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  133. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  134. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  135. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  136. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  137. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  138. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  139. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  140. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  141. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  142. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  143. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  144. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  145. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  146. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  147. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  148. Li J, et al. 2020. Elife. 9:00. PubMed
  149. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  150. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  151. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  152. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  153. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  154. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  155. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  156. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  157. Wan X, et al. 2018. Nature. 560:107. PubMed
  158. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  159. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  160. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  161. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  162. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  163. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  164. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  165. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  166. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  167. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  168. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  169. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  170. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  171. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  172. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  173. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  174. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  175. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  176. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  177. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  178. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  179. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  180. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  181. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  182. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  183. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  184. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  185. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  186. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  187. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  188. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  189. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  190. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  191. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  192. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  193. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  194. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  195. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  196. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  197. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  198. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  199. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  200. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  201. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  202. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  203. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  204. Long JT, et al. 2022. Elife. 11:. PubMed
  205. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  206. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  207. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  208. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  209. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  210. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  211. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  212. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  213. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  214. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  215. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  216. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  217. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  218. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  219. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  220. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  221. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  222. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  223. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  224. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  225. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  226. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  227. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  228. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  229. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  230. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  231. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  232. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  233. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  234. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  235. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  236. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  237. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  238. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  239. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  240. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  241. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  242. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  243. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  244. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  245. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  246. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  247. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  248. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  249. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  250. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  251. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  252. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  253. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  254. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  255. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  256. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  257. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  258. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  259. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  260. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  261. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  262. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  263. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  264. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  265. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  266. Sheng J, et al. 2021. eLife. 10:00. PubMed
  267. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  268. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  269. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  270. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  271. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  272. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  273. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  274. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  275. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  276. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  277. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
  278. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  279. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  280. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  281. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  282. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  283. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  284. Dingler FA, et al. 2020. Mol Cell. . PubMed
  285. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  286. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  287. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  288. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  289. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  290. Wolf Y, et al. 2019. Cell. 179:219. PubMed
RRID
AB_312972 (BioLegend Cat. No. 103107)
AB_312973 (BioLegend Cat. No. 103108)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05-14-2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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