Loading...

PE/Cyanine7 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
30-F11_PECy7_090507
C57BL/6 mouse splenocytes stained with 30-F11 PE/Cyanine7
  • 30-F11_PECy7_090507
    C57BL/6 mouse splenocytes stained with 30-F11 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
103113 25 µg 70€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
103114 100 µg 152€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  2. Rodriguez de la Fuente L, et al. 2021. STAR Protoc. 2:100841. PubMed
  3. Khare A, et al. 2016. Cell Rep. 15: 1700-1714. PubMed
  4. Garber C, et al. 2019. Nat Neurosci. 1.802777778. PubMed
  5. Dobie R, et al. 2020. Cell Reports. 29(7):1832-1847.e8.. PubMed
  6. Wu JH, et al. 2020. EMBO Mol Med. 12:e10154. PubMed
  7. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  8. Chen G, et al. 2021. J Mol Cell Cardiol. 159:62. PubMed
  9. Kfoury YS, et al. 2021. Cell Stem Cell. 28:2090. PubMed
  10. He D, et al. 2022. Immunity. 55:159. PubMed
  11. Tapanes S, et al. 2022. Glia. 70:1133. PubMed
  12. Kenney DJ, et al. 2022. Cell Rep. 39:110714. PubMed
  13. Jeong GU, et al. 2022. Microbiol Spectr. 10:e0109122. PubMed
  14. Kiani Shabestari S, et al. 2022. Cell Rep. 39:110961. PubMed
  15. Dong H, et al. 2022. Proc Natl Acad Sci U S A. 119:e2123247119. PubMed
  16. Steudler J, et al. 2022. Glia. 70:2045. PubMed
  17. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  18. Koizumi M, et al. 2022. J Biol Chem. 298:102506. PubMed
  19. Xuan FL, et al. 2022. Front Immunol. 13:1005067. PubMed
  20. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  21. Moiseeva V, et al. 2023. Nature. 613:169. PubMed
  22. An X, et al. 2023. Am J Reprod Immunol. 89:e13676. PubMed
  23. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  24. Taniguchi S, et al. 2023. Nat Commun. 14:143. PubMed
  25. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  26. Hattori Y, et al. 2023. Cell Rep. 42:112092. PubMed
  27. Ismailova A, et al. 2023. Front Immunol. 14:1123344. PubMed
  28. Zhao M, et al. 2023. J Nanobiotechnology. 21:50. PubMed
  29. Wei J, et al. 2022. Cancer Prev Res (Phila). 15:285. PubMed
  30. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  31. Narvaez del Pilar O, et al. 2022. Development. 149:. PubMed
  32. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  33. Hernandez BJ, et al. 2022. Am J Respir Cell Mol Biol. 67:389. PubMed
  34. Meyer T, et al. 2022. Proc Natl Acad Sci U S A. 119:e2211310119. PubMed
  35. Hong X, et al. 2022. Cell Stem Cell. 29:1298. PubMed
  36. Cronin SJF, et al. 2022. Sci Transl Med. 14:eabj1531. PubMed
  37. Mohamed GA, et al. 2023. Breast Cancer Res. 25:23. PubMed
  38. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  39. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  40. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  41. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  42. Tan X, et al. 2023. Adv Sci (Weinh). 10:e2206768. PubMed
  43. Sun JY, et al. 2023. Sci Adv. 9:eade4110. PubMed
  44. Zhang J, et al. 2023. Theranostics. 13:2226. PubMed
  45. Bobadilla Muñoz M, et al. 2023. Front Cell Dev Biol. 11:1128534. PubMed
  46. Hsieh MS, et al. 2023. NPJ Vaccines. 8:82. PubMed
  47. Zhang AQ, et al. 2023. Nat Biomed Eng. . PubMed
  48. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  49. Yokozeki Y, et al. 2021. Biomed Res Int. 2021:7988320. PubMed
  50. Schädlich IS, et al. 2022. iScience. 25:104470. PubMed
  51. Yang AC, et al. 2020. Nature. 583:425. PubMed
  52. Helms EJ, et al. 2021. Cancer Discov. Online ahead of print. PubMed
  53. Huck NA, et al. 2021. J Neurosci. 41:4349. PubMed
  54. Wu Q, et al. 2021. Cancer Commun (Lond). Online ahead of prin. PubMed
  55. Ma Q, et al. 2021. Clin Transl Immunology. 10:e1300. PubMed
  56. Yagishita Y, et al. 2020. Cell Mol Gastroenterol Hepatol. . PubMed
  57. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  58. Wagner G, et al. 2017. Sci Rep. 7:40881. PubMed
  59. Weeden C, et al. 2017. PLoS Biol. 10.1371/journal.pbio.2000731. PubMed
  60. Hilliard K, et al. 2015. Infect Immun . 83: 4015 - 4027. PubMed
  61. Shi Y, et al. 2020. Med Sci Monit. 26:e923328. PubMed
  62. Smith NR, et al. 2017. Cell Mol Gastroenterol Hepatol. 0.395138889. PubMed
  63. Zhou J, et al. 2019. Immunity. 50:403. PubMed
  64. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  65. Chang T, et al. 2017. PLoS Pathog. 10.1371/journal.ppat.1006485. PubMed
  66. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  67. García-Prat L, et al. 2020. Nat Cell Biol. 22:1307. PubMed
  68. Tatsuguchi T, et al. 2022. Int Immunol. 34:277. PubMed
  69. Pan J, et al. 2021. Mol Ther Nucleic Acids. 26:970. PubMed
  70. Vila Ellis L, et al. 2020. Dev Cell. 617:52. PubMed
  71. Kim YS, et al. 2021. Cell Death Dis. 12:307. PubMed
  72. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  73. Mansouri N, et al. 2019. JCI Insight. 4:e128060. PubMed
  74. Wilson RP, et al. 2019. PLoS Pathog. 15:e1007745. PubMed
  75. Barry KC, et al. 2018. Nat Med. 24:1178. PubMed
  76. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  77. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  78. Manivasagam S, et al. 2022. J Immunol. 208:1341. PubMed
  79. Saito S, et al. 2020. Nutrients. 12:. PubMed
  80. Fu Y, et al. 2020. Mol Ther. 1214:28. PubMed
  81. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  82. Greenberg J, et al. 2022. JCI Insight. Online ahead of print. PubMed
  83. White MPJ, et al. 2020. Front Immunol. 11:1830. PubMed
  84. Valds-Mora F, et al. 2021. Cell Reports. 35(2):108945. PubMed
  85. DellOrso S, et al. 2021. STAR Protocols. 2(2):100451. PubMed
  86. Little DR, et al. 2021. Nat Commun. 12:2509. PubMed
  87. Mathews J, et al. 2014. PLoS One. 9:97707. PubMed
  88. Britschgi A, et al. 2017. Nature. 541:541-545. PubMed
  89. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  90. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
  91. Kobayashi H, et al. 2020. STAR Protoc. 1:100078. PubMed
  92. Wang B, et al. 2017. EBioMedicine. 10.1016/j.ebiom.2017.03.041. PubMed
  93. Kaczmarek–Hájek K, et al. 2018. Elife. 7:e36217. PubMed
  94. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  95. Zheng L, et al. 2022. J Neuroinflammation. 19:128. PubMed
  96. Bhopale VM, et al. 2021. J Appl Physiol (1985). 130:1604. PubMed
  97. Campanario S, et al. 2021. Front Cell Dev Biol. 8:620409. PubMed
  98. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  99. Jiang YH, et al. 2020. J Mol Cell Cardiol. 138:115. PubMed
  100. Pan J, et al. 2020. J Neuroinflammation. 17:97. PubMed
  101. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  102. Garber C, et al. 2018. Nat Immunol. 19:151. PubMed
  103. Gigliotti J, et al. 2013. J Am Soc Nephrol. 24:1451. PubMed
  104. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  105. Galvão I, et al. 2018. Front Immunol. 9:142. PubMed
  106. Mizuochi C, et al. 2012. PLoS One. 7:e35763. PubMed
  107. Wang B,et al. 2017. Cell Discov.. 10.1038/celldisc.2017.36. PubMed
  108. Solanas G, et al. 2017. Cell. 170:678. PubMed
  109. Dubey LK, et al. 2019. Cell Rep. 27:2442. PubMed
  110. Zhu L, et al. 2021. Stem Cell Res Ther. 12:408. PubMed
  111. Bahar Halpern K, et al. 2020. Nat Commun. 11:1936. PubMed
  112. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  113. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  114. McGowan SE, et al. 2018. Am J Physiol Lung Cell Mol Physiol. 315:L102. PubMed
  115. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  116. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  117. Yang R, et al. 2022. Front Pharmacol. 13:774440. PubMed
  118. Fix DK, et al. 2021. Aging Cell. 20:e13448. PubMed
  119. Cassidy BR, et al. 2020. J Neuroinflammation. 17:259. PubMed
  120. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  121. Cain MP, et al. 2020. Dis Model Mech. 13:00. PubMed
  122. Court AC, et al. 2020. EMBO Rep. 21:e48052. PubMed
  123. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  124. Huang CH, et al. 2020. Adv Ther (Weinh). 3:. PubMed
  125. Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
  126. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  127. Allen S, et al. 2011. J Virol. 85:11448. PubMed
  128. Jaworska K, et al. 2015. J Immunol. 194:325. PubMed
  129. Furuya Y, et al. 2015. PLoS Pathog. 11: 1005180. PubMed
  130. Wang W, et al. 2020. Immunity. 51(6):1102-1118.e7.. PubMed
  131. Onder L et al. 2017. Immunity. 47(1):80-92 . PubMed
  132. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  133. Kimbrough D, et al. 2018. J Mol Cell Cardiol. 119:51. PubMed
  134. Codina A, et al. 2019. Cell Syst. 8:136. PubMed
  135. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  136. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  137. Basu A, et al. 2021. Cancer Immunol Res. Online ahead of print. PubMed
  138. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  139. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  140. McCoy S 2015. Am J Physiol Lung Cell Mol Physiol. 309: L463-L474. PubMed
  141. Yen Y, et al. 2008. J Virol. 82:12312. PubMed
  142. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  143. Son NH, et al. 2018. J Clin Invest. 128:4329. PubMed
  144. Ellegast JM, et al. 2022. Cancer Discov. 12:1760. PubMed
  145. Liu T, et al. 2022. Front Immunol. 13:901349. PubMed
  146. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  147. Manco R, et al. 2021. Nat Commun. 12:3074. PubMed
  148. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  149. Berg AL, et al. 2022. Cancers (Basel). 14:. PubMed
  150. Wang F, et al. 2021. Cell. 184(2):422-440.e17. PubMed
  151. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  152. Sela Y, et al. 2021. Elife. 10: . PubMed
  153. Ishii H, et al. 2012. Cell Death Dis. 9;3:e363. PubMed
  154. Kellish P, et al. 2019. J Clin Invest. 130:2279. PubMed
  155. Magri G et al. 2017. Immunity. 47(1):118-134 . PubMed
  156. Chu X, et al. 2021. Front Cell Dev Biol. 9:671841. PubMed
  157. Shafiei-Jahani P, et al. 2021. Nat Commun. 12:2526. PubMed
  158. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  159. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  160. Pascual G, et al. 2021. Nature. 599:485. PubMed
  161. Kolodziejczyk AA, et al. 2020. Nat Med. 26:1899. PubMed
  162. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  163. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  164. Evgin L, et al. 2020. Nat Commun. 2.671527778. PubMed
  165. van Gastel N, et al. 2020. Cell Metabolism. 32(3):391-403.e6. PubMed
  166. Wu X, et al. 2016. Sci Rep. 6:18685. PubMed
  167. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  168. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  169. Kobayashi H, et al. 2020. Cell Reports. 28(1):145-158.e9.. PubMed
  170. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  171. Jin L, et al. 2022. J Immunol Res. 2022:7222638. PubMed
  172. Koyama T, et al. 2022. Curr Issues Mol Biol. 44:3146. PubMed
  173. Evgin L, et al. 2022. Sci Transl Med. 14:eabn2231. PubMed
  174. Tang Z, et al. 2021. Stem Cell Res Ther. 12:397. PubMed
  175. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  176. Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
  177. Shen DD, et al. 2022. Mol Cancer. 21:75. PubMed
  178. Zhu J, et al. 2021. Cancer Cell Int. 21:529. PubMed
  179. Yuan M, et al. 2022. Oxid Med Cell Longev. 2022:5479491. PubMed
  180. Abdelfattah N, et al. 2022. Nat Commun. 13:767. PubMed
  181. Li J, et al. 2020. Development. :. PubMed
  182. Wang W, et al. 2021. STAR Protocols. 2(3):100756. PubMed
  183. Magness S, et al. 2013. Am J Physiol Gastrointest Liver Physiol. 305:542. PubMed
  184. Li S, et al. 2019. Front Neurol. 1.036805556. PubMed
  185. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  186. Mohammadpour H, et al. 2021. Cell Rep. 37:109883. PubMed
  187. Zhu S, et al. 2022. EBioMedicine. 80:104060. PubMed
  188. Sung PS, et al. 2022. JCI Insight. :. PubMed
  189. Zhang J, et al. 2022. Biomater Res. 26:44. PubMed
  190. Gu H, et al. 2021. Elife. 10:. PubMed
  191. Hendee K, et al. 2021. Aging (Albany NY). 13:7781. PubMed
  192. Issah Y, et al. 2021. Elife. 10:. PubMed
  193. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  194. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  195. Smith NR, et al. 2018. Cell Mol Gastroenterol Hepatol. 6:79. PubMed
  196. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  197. Nian Z, et al. 2021. Clin Cancer Res. 27:6026. PubMed
  198. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  199. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  200. Ognjenovic NB, et al. 2020. Dev Cell. 55:544. PubMed
  201. Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
  202. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  203. Béchade C, et al. 2020. Glia. . PubMed
  204. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  205. Boyce M, et al. 2022. Cells. 11:. PubMed
  206. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  207. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  208. Rai S, et al. 2022. Nat Commun. 13:5346. PubMed
  209. Fan X, et al. 2020. Acta Physiol (Oxf). 230:e13475. PubMed
  210. Fang Y, et al. 2022. Development. 149:. PubMed
  211. Rochford I, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 321:L686. PubMed
  212. Sheng J, et al. 2021. eLife. 10:00. PubMed
  213. Moreno M et al. 2014. The Journal of Neuroscience. 34(24):8175-85 . PubMed
  214. Nguyen HX et al. 2017. J Neurosci. 37(38):9269-9287 . PubMed
  215. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  216. Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
  217. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  218. Li Q, et al. 2022. J Biol Chem. :101753. PubMed
  219. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  220. Andreou T, et al. 2021. J Immunother Cancer. 9:. PubMed
  221. Gerner-Mauro KN, et al. 2020. Proc Natl Acad Sci U S A. 117:12182. PubMed
  222. Kimmel JC, et al. 2021. Cell Reports. 35(4):109046. PubMed
  223. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  224. Hussein M, et al. 2015. PLoS One. 10: 0135218. PubMed
  225. Gigliotti J, et al. 2015. J Am Soc Nephrol. 26: 2470 - 2481. PubMed
  226. Serr I, et al. 2016. Nat Commun. 7:10991. PubMed
  227. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
  228. Dourcy M, et al. 2020. Mucosal Immunol. 13:799. PubMed
  229. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  230. Song X, et al. 2021. FEBS Open Bio. 11:2453. PubMed
  231. Ren X, et al. 2021. Cell Death Dis. 12:484. PubMed
  232. Wu H, et al. 2020. Cell. 180(1):107-121.e17.. PubMed
  233. Muri J, et al. 2020. Cell Reports. 30(13):4399-4417. PubMed
  234. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  235. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  236. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
RRID
AB_312978 (BioLegend Cat. No. 103113)
AB_312979 (BioLegend Cat. No. 103114)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account